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Article

SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma.

Journal of translational medicine - 6 Oct 2015

Cui Xiao-Bin, Shen Yao-Yuan, Jin Ting-Ting, Li Su, Li Ting-Ting, Zhang Shu-Mao, Peng Hao, Liu Chun-Xia, Li Shu-Gang, Yang Lan, Li Na, Hu Jian-Ming, Jiang Jin-Fang, Li Man, Liang Wei-Hua, Li Yong, Wei Yu-Tao, Sun Zhen-Zhu, Wu Chuan-Yue, Chen Yun-Zhao, Li Feng

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a highly lethal cancer, and its underlying molecular mechanisms are poorly understood. Recent large-scale genome-wide association studies in Chinese Han populations have identified an ESCC susceptibility locus within the SLC39A6 gene. Here, we sought to explore the expression and biological function of SLC39A6 in ESCC. METHODS: Multiethnic validation of...

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Identifiers

PMID: 26444413
DOI: 10.1186/s12967-015-0681-z
PMCID: PMC4595240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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