Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Factors that differentiate cancer risk management decisions among females with pathogenic/likely pathogenic variants in PALB2, CHEK2, and ATM.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Nov 2023

Dean Marleah, Tezak Ann L, Johnson Sabrina, Weidner Anne, Almanza Deanna, Pal Tuya, Cragun Deborah L

Abstract excerpt

PURPOSE: Following disclosure of pathogenic or likely pathogenic variants in hereditary cancer genes, patients face cancer risk management decisions. Through this mixed-methods study, we investigated cancer risk management decisions among females with pathogenic or likely pathogenic variants in PALB2, CHEK2, and ATM to understand why some patients follow National Comprehensive Cancer Network guidelines, whereas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Checkpoint Kinase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fanconi Anemia Complementation Group N Protein

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Neoplasms

Share to Risk Management

Source

Identifiers

PMID: 37515473
DOI: 10.1016/j.gim.2023.100945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Factors that differentiate cancer risk management decisions among females with pathogenic/likely pathogenic variants in PALB2, CHEK2, and ATM.PMID 37515473Read ↗

Factors that influence the management recommendations breast surgeons provide to women with pathogenic variants in moderate penetrance breast cancer susceptibility genes.Semantic proximity Read ↗

Cancer risk management among female BRCA1/2, PALB2, CHEK2, and ATM carriers.Semantic proximity Read ↗

Toward a better understanding of the experience of patients with moderate penetrance breast cancer gene pathogenic/likely pathogenic variants: A focus on ATM and CHEK2.Semantic proximity Read ↗

Different Patterns of Risk Reducing Decisions in Affected or Unaffected BRCA Pathogenic Variant Carriers.Semantic proximity Read ↗

Gaps in Incorporating Germline Genetic Testing Into Treatment Decision-Making for Early-Stage Breast CancerSemantic proximity Read ↗

Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer RiskSemantic proximity Read ↗

Genetic testing and surgical treatment after breast cancer diagnosis: Results from a national online cohort.Semantic proximity Read ↗

Genetic testing and cancer risk management recommendations by physicians for at-risk relatives.Semantic proximity Read ↗

Uptake of Risk-Reducing Measures, Cascade Testing, and Related Challenges Among Carriers of Breast Cancer-Associated Germline Pathogenic Variants in Mexico.Semantic proximity Read ↗

Clinical management among individuals with variant of uncertain significance in hereditary cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

Uptake of Screening and Risk Reducing Recommendations Among Women with Hereditary Breast and Ovarian Cancer Syndrome Evaluated at a Large Urban Comprehensive Cancer CenterSemantic proximity Read ↗

"I wish that there was more info": characterizing the uncertainty experienced by carriers of pathogenic ATM and/or CHEK2 variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.