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3‐Mercaptopyruvate sulfurtransferase represses tumour progression and predicts prognosis in hepatocellular carcinoma

4 Mar 2022

Abstract excerpt

Abstract Background and Aims The prognosis of hepatocellular carcinoma (HCC) remains dismal, and its molecular pathogenesis has not been completely defined. The enzyme 3‐mercaptopyruvate sulfurtransferase (MPST) regulates endogenous hydrogen sulfide (H 2 S) biosynthesis. However, the role of MPST in HCC has never been intensively investigated. Methods MPST protein expression was analysed in HCC tumour tissues and...

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PMID: 35243746
DOI: 10.1111/liv.15228

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