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Regulation of neuronal autophagy and cell survival by MCL1 in Alzheimer’s disease

1 Jan 2022

Abstract excerpt

Maintaining neuronal integrity and function requires precise mechanisms controlling organelle and protein quality. Alzheimer’s disease (AD) is also characterized by functional defects in the clearance and recycling of intracellular components. In fact, neuronal homeostasis involves autophagy, mitophagy, apoptosis, and compromised activity in these cellular processes may cause pathological phenotypes of AD....

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PMID: 35233562
DOI: 10.15212/amm-2021-0002

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