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Compromised autophagy and mitophagy in brain ageing and Alzheimer’s diseases

1 Jan 2022

Abstract excerpt

Alzheimer's disease (AD) is one of the most persistent and devastating neurodegenerative disorders of old age, and is characterized clinically by an insidious onset and a gradual, progressive deterioration of cognitive abilities, ranging from loss of memory to impairment of judgement and reasoning. Despite years of research, an effective cure is still not available. Autophagy is the cellular 'garbage' clearance...

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PMID: 36908880
DOI: 10.1016/j.nbas.2022.100056

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