Article
Maternal and Adult Interleukin-17A Exposure and Autism Spectrum Disorder
8 Feb 2022
Abstract excerpt
Epidemiological evidence in humans has suggested that maternal infections and maternal autoimmune diseases are involved in the pathogenesis of autism spectrum disorder. Animal studies supporting human results have shown that maternal immune activation causes brain and behavioral alterations in offspring. Several underlying mechanisms, including interleukin-17A imbalance, have been identified. Apart from the...
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