Article
Polygenic risk for type 2 diabetes mellitus among individuals with psychosis and their relatives.
Journal of psychiatric research - 1 Jun 2016
Padmanabhan Jaya L, Nanda Pranav, Tandon Neeraj, Mothi Suraj S, Bolo Nicolas, McCarroll Steven, Clementz Brett A, Gershon Elliot S, Pearlson Godfrey D, Sweeney John A, Tamminga Carol A, Keshavan Matcheri S
Abstract excerpt
BACKGROUND: An elevated prevalence of Type 2 diabetes (T2D) has been observed in people with psychotic disorders and their relatives compared to the general population. It is not known whether this population also has increased genetic risk for T2D. METHODS: Subjects included probands with schizophrenia, schizoaffective disorder, or psychotic bipolar I disorder, their first-degree relatives without psychotic...
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