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Article

Neoantigens as potential vaccines in hepatocellular carcinoma

1 Feb 2022

Abstract excerpt

BACKGROUND: Neoantigens, new immunogenic sequences arising from tumor mutations, have been associated with response to immunotherapy and are considered potential targets for vaccination. Hepatocellular carcinoma (HCC) is a moderately mutated tumor, where the neoantigen repertoire has not been investigated. Our aim was to analyze whether tumors in HCC patients contain immunogenic neoantigens suitable for future...

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PMID: 35193931
DOI: 10.1136/jitc-2021-003978

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