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Dissecting the molecular control of immune cell accumulation in the inflamed joint

22 Feb 2022

Abstract excerpt

Mechanisms governing entry and exit of immune cells into and out of inflamed joints remain poorly understood. We sought herein to identify the key molecular pathways regulating such migration. Using murine models of inflammation in conjunction with mice expressing a photoconvertible fluorescent protein, we characterized the migration of cells from joints to draining lymph nodes and performed RNA-Seq analysis on...

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PMID: 35192549
DOI: 10.1172/jci.insight.151281

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