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Article

Associations of common genetic risk variants of the muscarinic acetylcholine receptor M2 with cardiac autonomic dysfunction in patients with schizophrenia.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2023

Refisch Alexander, Komatsuzaki Shoko, Ungelenk Martin, Chung Ha-Yeun, Schumann Andy, Schilling Susann S, Jantzen Wibke, Schröder Sabine, Mühleisen Thomas W, Nöthen Markus M, Hübner Christian A, Bär Karl-Jürgen

Abstract excerpt

OBJECTIVES: Decreased vagal modulation, which has consistently been observed in schizophrenic patients, might contribute to increased cardiac mortality in schizophrenia. Previously, associations between CHRM2 (Cholinergic Receptor Muscarinic 2) and cardiac autonomic features have been reported. Here, we tested for possible associations between these polymorphisms and heart rate variability in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35172679
DOI: 10.1080/15622975.2022.2043561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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