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Article

Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment.

PLoS pathogens - 1 Sept 2016

Maroui Mohamed Ali, Callé Aleth, Cohen Camille, Streichenberger Nathalie, Texier Pascale, Takissian Julie, Rousseau Antoine, Poccardi Nolwenn, Welsch Jérémy, Corpet Armelle, Schaeffer Laurent, Labetoulle Marc, Lomonte Patrick

Abstract excerpt

Herpes simplex virus 1 (HSV-1) establishes latency in trigeminal ganglia (TG) sensory neurons of infected individuals. The commitment of infected neurons toward the viral lytic or latent transcriptional program is likely to depend on both viral and cellular factors, and to differ among individual neurons. In this study, we used a mouse model of HSV-1 infection to investigate the relationship between viral genomes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mice, Inbred BALB C

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Source

Open in PubMed Open full text

Identifiers

PMID: 27618691
DOI: 10.1371/journal.ppat.1005834
PMCID: PMC5019400

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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