Article
Plasmid-based CRISPR-Cas9 system efficacy for introducing targeted mutations in CD81 gene of MDA-MB-231 cell line.
Folia histochemica et cytobiologica - 1 Jan 2022
Arbabi Zaboli Kasra, Rahimi Hossein, Thekkiniath Jose, Taromchi Amir Hossein, Kaboli Saeed
Abstract excerpt
INTRODUCTION: Breast cancer has been represented a challenging issue worldwide as it is one of the major leading causes of death among women. CD81 gene, a member of the tetraspanin protein family, has been associated with the development of human cancers. Genome editing technologies, particularly the CRISPR-Cas9 system, have shown rapid progress in gene function studies. In this study, we aimed to evaluate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.