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Article

Characterization of Axon Guidance Phenotypes in Wnt/PCP Mutant Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Miller Kathryn M, Marfull-Oromí Pau, Zou Yimin

Abstract excerpt

Our lab showed that the Wnt family proteins can function as axon guidance molecules and the planar cell polarity (PCP) pathway mediates the function of Wnts in axon guidance. One of the key evidences was by identifying the axon guidance defects in knockout or conditional knockout animals. We utilized a variety of axon tracing and labeling techniques, including immunohistochemistry (IHC), DiI, BDA, and fluorescent...

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Identifiers

PMID: 35147948
DOI: 10.1007/978-1-0716-2035-9_17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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