Article
RhoGDI2 induced malignant phenotypes of pancreatic cancer cells via regulating Snail expression.
Genes & genomics - 1 May 2022
Yi Bin, Hu You, Zhu Dongming, Yao Jun, Zhou Jian, Zhang Yi, He Zhilong, Zhang Lifeng, Zhang Zixiang, Yang Jian, Tang Yuchen, Huang Yujie, Li Dechun, Liu Qiuhua
Abstract excerpt
BACKGROUND: Rho GDP dissociation inhibitor 2 (RhoGDI2) has been shown to contribute to the aggressive phenotypes of human cancers, such as tumor metastasis and chemoresistance. OBJECTIVE: This study aimed to assess the effects of RhoGDI2 on tumor progression and chemoresistance in pancreatic cancer cells. METHODS: The expression of RhoGDI2 in pancreatic cancer cells was detected by Western blot analysis....
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