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Article

Dominant role of CACNA1D exon mutations for blood pressure regulation.

Journal of hypertension - 1 Apr 2022

Wang Huan, Zhu Jing-Kang, Cheng Lan, Mao Gaowei, Chen Hong, Wu Xiaoying, Hong Huiwu, Wang Canwang, Lin Pengcheng, Chen Jie, Maboh Rene Nfornah, Chen Hui

Abstract excerpt

BACKGROUND: CACNA1D gene, which encodes the α1 subunit of the Cav1.3 L-type calcium channel effectively regulates intracellular Ca2+ stability. In recent years, clinical studies have shown that the CACNA1D polymorphisms were associated with hypertension. OBJECTIVE: The purpose of this study was to evaluate the effects of CACNA1D exon mutation on blood pressure (BP) in Sprague-Dawley rats. METHODS: The rats with...

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Identifiers

PMID: 35142739
DOI: 10.1097/HJH.0000000000003085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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