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NOS3 gene intron 4 a/b polymorphism is associated with ESRD in autosomal dominant polycystic kidney disease patients.

Jornal brasileiro de nefrologia - 1 Jan 2000

Padhi Udit Narayan, Mulkalwar Madhubala, Saikrishna Lakkakula, Verma Henu Kumar, Bhaskar Lvks

Abstract excerpt

INTRODUCTION: Endothelial nitric oxide synthase (eNOS) genes have been implicated in renal hemodynamics as potent regulators of vascular tone and blood pressure. It has been linked to a reduction in plasma nitric oxide levels. Several studies have recently been conducted to investigate the role of NOS3 gene polymorphisms and end-stage renal disease (ESRD). However, the results are still unclear and the mechanisms...

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Share to Genetic Predisposition to Disease
Share to Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Nitric Oxide Synthase Type III

Share to Polycystic Kidney, Autosomal Dominant

Share to Polymorphism, Genetic

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Identifiers

PMID: 35138322
DOI: 10.1590/2175-8239-JBN-2021-0089
PMCID: PMC9269174

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