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Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases

13 Mar 2019

Abstract excerpt

Numerous studies have demonstrated that endothelial cells are capable of undergoing endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular transdifferentiation. EndMT is a complex biological process in which endothelial cells adopt a mesenchymal phenotype displaying typical mesenchymal cell morphology and functions, including the acquisition of cellular motility and contractile...

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PMID: 30864875
DOI: 10.1152/physrev.00021.2018

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