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Article

Familial coaggregation and shared genetic influence between major depressive disorder and gynecological diseases.

European journal of epidemiology - 1 Oct 2024

Chen Cheng-Yun, Cheng Chi-Fung, Chen Pei-Chun, Wu Chi-Shin, Lin Mei-Chen, Su Mei-Hsin, Chang Cherry Yin-Yi, Pan Yi-Jiun, Huang Yen-Tsung, Fan Chun-Chieh, Wang Shi-Heng

Abstract excerpt

The mechanism underlying the co-occurrence of major depressive disorder (MDD) and gynecological diseases remains unclear. This study aimed to investigate the familial co-aggregation and shared genetic loading between MDD and gynecological diseases, namely dysmenorrhea, endometriosis, uterine leiomyomas (UL), and polycystic ovary syndrome (PCOS). Overall, 2,121,632 females born 1970-1999 with parental information...

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PMID: 39495462
DOI: 10.1007/s10654-024-01166-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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