Article
Single nucleotide polymorphisms in binding site of miRNA-135a and targeted gene IRS2 are correlated with multiple clinical features of PCOS: A study in Chinese women.
Technology and health care : official journal of the European Society for Engineering and Medicine - 1 Jan 2022
Gu Heng, Li Longyu, Zhou Bingyi, Li Mingzhen, Zhong Wenyao, Wei Xiangcai, Zhong Xingmin
Abstract excerpt
BACKGROUND: The etiology of polycystic ovary syndrome (PCOS) remains unclear with highly heterogeneous clinical manifestations, recently growing evidence revealing genetic variants play a crucial part in its pathogenesis. OBJECTIVE: This study aimed to examine the correlation between SNPs in miRNA-135a's binding site of targeted gene IRS2 and clinical manifestations of PCOS in Chinese females. METHOD: A total of...
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