Article
Association study to evaluate Foxo1 and Foxo3 gene polymorphisms in polycystic ovary syndrome: a preliminary case-control study and in silico analysis.
Molecular biology reports - 1 Apr 2023
Rakhshani Nejad Arghavan, Sargazi Saman, Ghasemi Marzieh, Samareh Moosavi Saeedeh, Heidari Nia Milad, Saravani Ramin
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is known as a multifactorial and multi-gene-mediated endocrine disorder among women of reproductive age. FoxO1 and FoxO3 are members of the forkhead transcriptional factors family that play a pivotal role in the function of ovaries. The current work is aimed at investigating the association between gene variants of FoxO1 and FoxO3 and the risk of PCOS in a sample of...
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