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Update on the effects of energy metabolism in bone marrow mesenchymal stem cells differentiation

1 Feb 2022

Abstract excerpt

BACKGROUND: As common progenitor cells of osteoblasts and adipocytes, bone marrow mesenchymal (stromal) stem cells (BMSCs) play key roles in bone homeostasis, tissue regeneration, and global energy homeostasis; however, the intrinsic mechanism of BMSC differentiation is not well understood. Plasticity in energy metabolism allows BMSCs to match the divergent demands of osteo-adipogenic differentiation. Targeting...

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PMID: 35121170
DOI: 10.1016/j.molmet.2022.101450

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