Article
Association of HLA-DM and HLA class II genes with antibody response induced by inactivated Japanese encephalitis vaccine.
HLA - 1 Apr 2022
He Jihong, Chen Jun, Han Xue, Gu Qin, Liang Jiangli, Sun Mingbo, Liu Shuyuan, Yao Yufeng, Shi Li
Abstract excerpt
HLA class II molecules, HLA-DR, DP and DQ, together with HLA II-like protein DM, play a dominant role in the processing and presentation of antigens, which may influence vaccine effectiveness. We previously demonstrated that variations in the HLA-DRB1, DPB1 and DQB1 genes may affect the neutralising antibody (NAb) response induced by the inactivated Japanese encephalitis vaccine (IJEV). In the present study, we...
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