Clinical Utility of Germline Genetic Testing in Japanese Men Undergoing Prostate Biopsy.

doi:10.1093/jncics/pkac001

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Article

Clinical Utility of Germline Genetic Testing in Japanese Men Undergoing Prostate Biopsy.

JNCI cancer spectrum - 1 Feb 2022

Akamatsu Shusuke, Terada Naoki, Takata Ryo, Kinoshita Hidefumi, Shimatani Kimihiro, Momozawa Yukihide, Yamamoto Michio, Tada Harue, Kawamorita Naoki, Narita Shintaro, Kato Takuma, Nitta Masahiro, Kandori Shuya, Koike Yusuke, Inazawa Johji, Kimura Takahiro, Kimura Hiroko, Kojima Takahiro, Terachi Toshiro, Sugimoto Mikio, Habuchi Tomonori, Arai Yoichi, Yamamoto Shingo, Matsuda Tadashi, Obara Wataru, Kamoto Toshiyuki, Inoue Takahiro, Nakagawa Hidewaki, Ogawa Osamu

Abstract excerpt

Background: Multiple common variants and also rare variants in monogenic risk genes such as BRCA2 and HOXB13 have been reported to be associated with risk of prostate cancer (PCa); however, the clinical setting in which germline genetic testing could be used for PCa diagnosis remains obscure. Herein, we tested the clinical utility of a 16 common variant-based polygenic risk score (PRS) that has been developed...

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Identifiers

PMID: 35118230
DOI: 10.1093/jncics/pkac001
PMCID: PMC8807580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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