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Canonical Wnt Signaling in the Pathology of Iron Overload‐Induced Oxidative Stress and Age‐Related Diseases

1 Jan 2022

Abstract excerpt

Iron accumulates in the vital organs with aging. This is associated with oxidative stress, inflammation, and mitochondrial dysfunction leading to age-related disorders. Abnormal iron levels are linked to neurodegenerative diseases, liver injury, cancer, and ocular diseases. Canonical Wnt signaling is an evolutionarily conserved signaling pathway that regulates many cellular functions including cell proliferation,...

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PMID: 35116092
DOI: 10.1155/2022/7163326

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