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Article

High frequency of PDGFRA and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: a glimmer of hope?

Journal of translational medicine - 2 Feb 2022

Hu Wanming, Duan Hao, Zhong Sheng, Zeng Jing, Mou Yonggao

Abstract excerpt

BACKGROUND: Diffuse hemispheric glioma H3 G34-mutant (G34-DHG) is a new type of pediatric-type diffuse high-grade glioma in the fifth edition of the WHO Classification of Tumors of the Central Nervous System. The current treatment for G34-DHG involves a combination of surgery and conventional radiotherapy or chemotherapy; however, the therapeutic efficacy of this approach is not satisfactory. In recent years,...

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Identifiers

PMID: 35109850
DOI: 10.1186/s12967-022-03258-1
PMCID: PMC8812218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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