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Article

Hemispherical Pediatric High-Grade Glioma: Molecular Basis and Therapeutic Opportunities

17 Dec 2020

Abstract excerpt

In this review, we discuss the molecular characteristics, development, evolution, and therapeutic perspectives for pediatric high-grade glioma (pHGG) arising in cerebral hemispheres. Recently, the understanding of biology of pHGG experienced a revolution with discoveries arising from genomic and epigenomic high-throughput profiling techniques. These findings led to identification of prevalent molecular...

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PMID: 33348922
DOI: 10.3390/ijms21249654

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