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Matrix metalloproteinases 7, 8, 12, 13 gene haplotypes associated with colorectal cancer in a Mexican population.

Gaceta medica de Mexico - 1 Jan 2021

Moreno-Ortiz José M, Gutiérrez-Angulo Melva, Ramírez-Ramírez Ruth, González-Mercado Anahí, Suárez-Villanueva Alexis S, Partida-Pérez Miriam, Maciel-Gutiérrez Víctor, Ayala-Madrigal Ma de la Luz

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMPs) are involved in tumor invasion and progression in colorectal cancer (CRC). Variants rs11568818, rs11225395, rs2276109 and rs2252070 have been associated with this neoplasm. OBJECTIVE: To evaluate MMPs 7, 8, 12, and 13 haplotypes and their association with CRC. MATERIAL AND METHODS: One-hundred and four patients and 112 healthy individuals were genotyped by polymerase...

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PMID: 35104263
DOI: 10.24875/GMM.M21000609

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