Article
Gene polymorphism of matrix metalloproteinase-12 and -13 and association with colorectal cancer in Swedish patients.
Anticancer research - 1 Aug 2013
VAN Nguyen Song, Skarstedt Marita, Löfgren Sture, Zar Niklas, Andersson Roland E, Lindh Mikael, Matussek Andreas, Dimberg Jan
Abstract excerpt
BACKGROUND: It has been widely reported that matrix metalloproteinases (MMPs) have fundamental roles in pathological processes in cancer through degradation of basal membranes and extracellular matrix. For MMP12 and MMP13, a functional single nucleotide polymorphism (SNP) has been detected -82A →...
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