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T cell responses to SARS-CoV-2 spike cross-recognize Omicron

31 Jan 2022

Abstract excerpt

Abstract The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations 1,2 that contribute to viral escape from antibody neutralization 3–6 and reduce vaccine protection from infection 7,8 . The extent to which other components of the adaptive response such as T cells may still target Omicron and contribute to protection from severe outcomes is unknown. Here we assessed the ability of T cells to...

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PMID: 35102311
DOI: 10.1038/s41586-022-04460-3

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