Article
The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.
Cellular and molecular life sciences : CMLS - 31 Jan 2022
Wang Li-Na, Wang Li, Cheng Guanghui, Dai Mingkai, Yu Yunhai, Teng Guoxin, Zhao Jingjie, Xu Dawei
Abstract excerpt
The role of telomerase reverse transcriptase (TERT) induction and telomere maintenance in carcinogenesis including cervical cancer (CC) pathogenesis has been well established. However, it remains unclear whether they affect infection of high-risk human papillomavirus (hrHPV), an initiating event for CC development. Similarly, genetic variants at the TERT locus are shown to be associated with susceptibility to CC,...
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