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Article

HIV-1-Specific Immunodominant T-Cell Responses Drive the Dynamics of HIV-1 Recombination Following Superinfection.

Frontiers in immunology - 1 Jan 2021

Zhang Hui, Cao Shuang, Gao Yang, Sun Xiao, Jiang Fanming, Zhao Bin, Ding Haibo, Dong Tao, Han Xiaoxu, Shang Hong

Abstract excerpt

A series of HIV-1 CRF01_AE/CRF07_BC recombinants were previously found to have emerged gradually in a superinfected patient (patient LNA819). However, the extent to which T-cell responses influenced the development of these recombinants after superinfection is unclear. In this study, we undertook a recombination structure analysis of the gag, pol, and nef genes from longitudinal samples of patient LNA819. A total...

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Identifiers

PMID: 35095925
DOI: 10.3389/fimmu.2021.820628
PMCID: PMC8794799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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