Article
Gut microbiome variation is associated to Multiple Sclerosis phenotypic subtypes.
Annals of clinical and translational neurology - 1 Apr 2020
Reynders Tatjana, Devolder Lindsay, Valles-Colomer Mireia, Van Remoortel Ann, Joossens Marie, De Keyser Jacques, Nagels Guy, D'hooghe Marie, Raes Jeroen
Abstract excerpt
OBJECTIVE: Multiple sclerosis (MS) is a heterogenous, inflammatory disease of the central nervous system. Microbiota alterations in MS versus healthy controls (HC) are observed, but results are inconsistent. We studied diversity, enterotypes, and specific gut microbial taxa variation between MS and HC, and between MS subgroups. METHODS: Amplicon sequencing of the 16S ribosomal RNA V4 region (Illumina MiSeq) was...
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