Article
Genetic variants in obesity-related genes and the risk of osteoporotic fracture. The Hortega Follow-up Study.
Frontiers in bioscience (Landmark edition) - 18 Jan 2022
Usategui-Martín Ricardo, Pérez-Castrillón Jose Luis, Briongos-Figuero Laisa, Abadía-Otero Jesica, Lara-Hernandez Francisco, García-Sorribes Soraya, Martín-Vallejo Javier, García-García Ana B, Chaves Felipe J, Martín-Escudero Juan Carlos
Abstract excerpt
BACKGROUND: Osteoporosis and obesity are major public health problems that are closely correlated, as they share various features, including a genetic predisposition. A genetic correlation between obesity and osteoporosis due to the biological common pathways of bone and fat metabolism, which implies pleiotropic genes regulating has been described. The objective of our study was to analyse whether polymorphisms...
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