Article
Epigenetic Modifications Linked to T2D, the Heritability Gap, and Potential Therapeutic Targets.
Biochemical genetics - 1 Dec 2018
Szabó Monica, Máté Beáta, Csép Katalin, Benedek Theodora
Abstract excerpt
With the pandemic of type 2 diabetes (T2D), there is an ever-increasing need to fully understand the underlying mechanisms of the disease. Type 2 diabetes shows a high heritability risk (25-80%); however, genes account only for 10% of this risk. From all the risk factors for diabetes, epigenetic mechanisms have the highest statistical scoring in explaining the disease. A multitude of organ-specific epigenomic...
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