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Article

The estimates of effective population size based on linkage disequilibrium are virtually unaffected by natural selection.

PLoS genetics - 1 Jan 2022

Novo Irene, Santiago Enrique, Caballero Armando

Abstract excerpt

The effective population size (Ne) is a key parameter to quantify the magnitude of genetic drift and inbreeding, with important implications in human evolution. The increasing availability of high-density genetic markers allows the estimation of historical changes in Ne across time using measures of genome diversity or linkage disequilibrium between markers. Directional selection is expected to reduce diversity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35077457
DOI: 10.1371/journal.pgen.1009764
PMCID: PMC8815936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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