Article
Recent human effective population size estimated from linkage disequilibrium.
Genome research - 1 Apr 2007
Tenesa Albert, Navarro Pau, Hayes Ben J, Duffy David L, Clarke Geraldine M, Goddard Mike E, Visscher Peter M
Abstract excerpt
Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present the first genome-wide estimates of human effective population size from LD data. Chromosome-specific effective population size was estimated for all autosomes and the X chromosome from estimated LD between SNP pairs <100 kb apart. We account for variation in...
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