Article
Estimation of historical effective population size using linkage disequilibria with marker data.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Aug 2012
Corbin L J, Liu A Y H, Bishop S C, Woolliams J A
Abstract excerpt
Theory hypothesizes that the rate of decline in linkage disequilibrium (LD) as a function of distance between markers, measured by r(2), can be used to estimate effective population size (N(e)) and how it varies over time. The development of high-density genotyping makes feasible the application...
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