Article
The European Prevalence of Resistance Associated Substitutions among Direct Acting Antiviral Failures.
Viruses - 22 Dec 2021
Popping Stephanie, Cento Valeria, Seguin-Devaux Carole, Boucher Charles A B, de Salazar Adolfo, Heger Eva, Mor Orna, Sayan Murat, Salmon-Ceron Dominique, Weis Nina, Krarup Henrik B, de Knegt Robert J, Săndulescu Oana, Chulanov Vladimir, van de Vijver David A M C, García Federico, Ceccherini-Silberstein Francesca
Abstract excerpt
Background: Approximately 71 million people are still in need of direct-acting antiviral agents (DAAs). To achieve the World Health Organization Hepatitis C elimination goals, insight into the prevalence and influence of resistance associated substitutions (RAS) is of importance. Collaboration is key since DAA failure is rare and real-life data are scattered. We have established a European collaboration, HepCare,...
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