Article
Tracking SARS-CoV-2 Spike Protein Mutations in the United States (January 2020-March 2021) Using a Statistical Learning Strategy.
Viruses - 21 Dec 2021
Zhao Lue Ping, Lybrand Terry P, Gilbert Peter B, Hawn Thomas R, Schiffer Joshua T, Stamatatos Leonidas, Payne Thomas H, Carpp Lindsay N, Geraghty Daniel E, Jerome Keith R
Abstract excerpt
The emergence and establishment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of interest (VOIs) and variants of concern (VOCs) highlight the importance of genomic surveillance. We propose a statistical learning strategy (SLS) for identifying and spatiotemporally tracking potentially relevant Spike protein mutations. We analyzed 167,893 Spike protein sequences from coronavirus disease...
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