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Sequence Similarity Network Analysis Provides Insight into the Temporal and Geographical Distribution of Mutations in SARS-CoV-2 Spike Protein.

Viruses - 29 Jul 2022

Patil Shruti S, Catanese Helen N, Brayton Kelly A, Lofgren Eric T, Gebremedhin Assefaw H

Abstract excerpt

Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), which still infects hundreds of thousands of people globally each day despite various countermeasures, has been mutating rapidly. Mutations in the spike (S) protein seem to play a vital role in viral stability, transmission, and adaptability. Therefore, to control the spread of the virus, it is important to gain insight into the evolution and...

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PMID: 36016294
DOI: 10.3390/v14081672
PMCID: PMC9413517

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