Article
Synergetic Fermentation of Glucose and Glycerol for High-Yield N-Acetylglucosamine Production in Escherichia coli.
International journal of molecular sciences - 11 Jan 2022
Wang Kaikai, Wang Xiaolu, Luo Huiying, Wang Yaru, Wang Yuan, Tu Tao, Qin Xing, Bai Yingguo, Huang Huoqing, Yao Bin, Su Xiaoyun, Zhang Jie
Abstract excerpt
N-acetylglucosamine (GlcNAc) is an amino sugar that has been widely used in the nutraceutical and pharmaceutical industries. Recently, microbial production of GlcNAc has been developed. One major challenge for efficient biosynthesis of GlcNAc is to achieve appropriate carbon flux distribution between growth and production. Here, a synergistic substrate co-utilization strategy was used to address this challenge....
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