Article

Combinatorial modular pathway engineering for guanosine 5′-diphosphate-L-fucose production in recombinant Escherichia coli

2020-01-14

Abstract excerpt

<h4>Background: </h4> Guanosine 5′-diphosphate (GDP)-L-fucose is a vital nucleotide sugar involved in the synthesis of fucosylated oligosaccharides, such as fucosylated human milk oligosaccharides, which play important roles in physiological and pathological processes. <h4>Results: </h4>: In this study, a combinatorial modular pathway engineering strategy was implemented to efficiently increase the intracellular t...

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Literature Corpus work: 37829dbc-e463-592c-9d0b-76c3529c6c5f
DOI: 10.21203/rs.2.20808/v1

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