Article
Transcriptome profiling of a novel Enterobacter aerogenes mutant with mannose-rich exopolysaccharide phenotype induced by phosphoenolpyruvate carboxylase inactivation.
Applied and environmental microbiology - 22 Apr 2026
Peng Xinru, Chen Jiale, Ding Yilin, Bai Ruoxuan, Lu Ping, Xu Fangxu, Zeng Guohong, Zhao Hongxin
Abstract excerpt
Mannose, a common monosaccharide with primary functions in protein glycosylation and immune regulation, has been widely used in medicine, cosmetics, and food additives, increasing its economic value. In our study, the ppc gene was knocked out in Enterobacter aerogenes IAM1183 to regulate phosphoenolpyruvate carboxylase activity, thereby optimizing hydrogen-producing metabolism. Unexpectedly, the mutant strain...
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