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Article

Molecular Mechanisms in Pentanucleotide Repeat Diseases.

Cells - 8 Jan 2022

Loureiro Joana R, Castro Ana F, Figueiredo Ana S, Silveira Isabel

Abstract excerpt

The number of neurodegenerative diseases resulting from repeat expansion has increased extraordinarily in recent years. In several of these pathologies, the repeat can be transcribed in RNA from both DNA strands producing, at least, one toxic RNA repeat that causes neurodegeneration by a complex mechanism. Recently, seven diseases have been found caused by a novel intronic pentanucleotide repeat in distinct genes...

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Identifiers

PMID: 35053321
DOI: 10.3390/cells11020205
PMCID: PMC8773600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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