Article
High-speed fluorescence image-enabled cell sorting.
Science (New York, N.Y.) - 21 Jan 2022
Schraivogel Daniel, Kuhn Terra M, Rauscher Benedikt, Rodríguez-Martínez Marta, Paulsen Malte, Owsley Keegan, Middlebrook Aaron, Tischer Christian, Ramasz Beáta, Ordoñez-Rueda Diana, Dees Martina, Cuylen-Haering Sara, Diebold Eric, Steinmetz Lars M
Abstract excerpt
Fast and selective isolation of single cells with unique spatial and morphological traits remains a technical challenge. Here, we address this by establishing high-speed image-enabled cell sorting (ICS), which records multicolor fluorescence images and sorts cells based on measurements from image data at speeds up to 15,000 events per second. We show that ICS quantifies cell morphology and localization of labeled...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.