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Article

An in-silico analysis to identify structural, functional and regulatory role of SNPs in hMRE11.

Journal of biomolecular structure & dynamics - 1 Apr 2023

Tarapara Bhoomi, Shah Franky

Abstract excerpt

Meiotic recombination 11 (MRE11) is a component of the tri-molecular MRE11-RAD50-NBS1 (MRN) complex, which functions as an exonuclease and endonuclease which is involved in identifying, signalling, protecting and repairing double-strand breaks in DNA (DSBs). Ataxia-telangiectasia-like disorder (ATLD) 1 and Nijmegen breakage syndrome (NBS)-like disorder are MRE11 associated diseases. In the present study, we used...

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Identifiers

PMID: 35048780
DOI: 10.1080/07391102.2022.2028678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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