Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation and single-nucleotide polymorphisms in DDX58 are associated with hand, foot and mouth disease caused by enterovirus 71.

PLoS neglected tropical diseases - 1 Jan 2022

Li Ya-Ping, Liu Chen-Rui, Deng Hui-Ling, Wang Mu-Qi, Tian Yan, Chen Yuan, Zhang Yu-Feng, Dang Shuang-Suo, Zhai Song

Abstract excerpt

BACKGROUND: This research aimed to explore the association between the RIG-I-like receptor (RIG-I and MDA5 encoded by DDX58 and IFIH1, respectively) pathways and the risk or severity of hand, foot, and mouth disease caused by enterovirus 71 (EV71-HFMD). In this context, we explored the influence of gene methylation and polymorphism on EV71-HFMD. METHODOLOGY/PRINCIPAL FINDINGS: 60 healthy controls and 120...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DEAD Box Protein 58

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Enterovirus A, Human

Share to Hand, Foot and Mouth Disease

Share to Interferon-Induced Helicase, IFIH1

Share to Receptors, Immunologic

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 35041675
DOI: 10.1371/journal.pntd.0010090
PMCID: PMC8765647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation and single-nucleotide polymorphisms in DDX58 are associated with hand, foot and mouth disease caused by enterovirus 71.PMID 35041675Read ↗

DNA methylation and SNP in IFITM3 are correlated with hand, foot and mouth disease caused by enterovirus 71.Semantic proximity Read ↗

Association of gene polymorphisms of pattern-recognition receptor signaling pathway with the risk and severity of hand, foot, and mouth disease caused by enterovirus 71 in Chinese Han population.Semantic proximity Read ↗

A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection.Semantic proximity Read ↗

[Polymorphisms of TLR7 rs3853839 and rs179010 are associated with susceptibility to and severity of hand, foot and mouth disease caused by enterovirus 71 in male children].Semantic proximity Read ↗

Molecular epidemiology and clinical characteristics of enteroviruses associated HFMD in Chengdu, China, 2013–2022Semantic proximity Read ↗

Epidemics and aetiology of hand, foot and mouth disease in Xiamen, China, from 2008 to 2015Semantic proximity Read ↗

Study on long noncoding RNA in enterovirus 71-induced severe hand-foot-mouth diseaseSemantic proximity Read ↗

TLR3 polymorphisms are associated with the severity of hand, foot, and mouth disease caused by enterovirus A71 in a Chinese children population.Semantic proximity Read ↗

Association of TLR3 gene 1377C/T (rs3775290) and TLR7 gene C/G (rs3853839) polymorphism with hand, foot, and mouth disease caused by human enterovirus 71 infection susceptibility and severity in the Chinese Han population: A meta-analysis of case-control studies.Semantic proximity Read ↗

Association of IFIH1 and DDX58 genes polymorphism with susceptibility to COVID-19.Semantic proximity Read ↗

Pathogenic characteristics of hand, foot and mouth disease in Shaanxi Province, China, 2010-2016.Semantic proximity Read ↗

Association of gene polymorphisms of CD55 with susceptibility to and severity of hand, foot, and mouth disease caused by enterovirus 71 in the Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.