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Regulation of gliotoxin biosynthesis and protection in Aspergillus species

18 Jan 2022

Abstract excerpt

Aspergillus fumigatus causes a range of human and animal diseases collectively known as aspergillosis. A. fumigatus possesses and expresses a range of genetic determinants of virulence, which facilitate colonisation and disease progression, including the secretion of mycotoxins. Gliotoxin (GT) is the best studied A. fumigatus mycotoxin with a wide range of known toxic effects that impair human immune cell...

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PMID: 35041649
DOI: 10.1371/journal.pgen.1009965

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