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Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains

2 Dec 2021

Abstract excerpt

Heteroresistance can lead to treatment failure and is difficult to detect by the methods currently employed by clinical laboratories. The aim of this study was to investigate the prevalence of the amikacin-heteroresistant Klebsiella pneumoniae strains and explore potential amikacin heteroresistance mechanism through whole-genome sequencing (WGS) and quantitative reverse-transcription PCR (qRT-PCR). In this study,...

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Share to Antibiotic Resistance in Bacteria
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PMID: 35035381
DOI: 10.3389/fmicb.2021.682239

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