Article
Genomic Characterization of Colistin Heteroresistance in Klebsiella pneumoniae during a Nosocomial Outbreak.
Antimicrobial agents and chemotherapy - 1 Nov 2016
Halaby Teysir, Kucukkose Emre, Janssen Axel B, Rogers Malbert R C, Doorduijn Dennis J, van der Zanden Adri G M, Al Naiemi Nashwan, Vandenbroucke-Grauls Christina M J E, van Schaik Willem
Abstract excerpt
Klebsiella pneumoniae is emerging as an important nosocomial pathogen due to its rapidly increasing multidrug resistance, which has led to a renewed interest in polymyxin antibiotics, such as colistin, as antibiotics of last resort. However, heteroresistance (i.e., the presence of a subpopulation of resistant bacteria in an otherwise susceptible culture) may hamper the effectiveness of colistin treatment in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.